Join us at the 13th annual PEGS Boston!

Going to PEGS Boston? Drop by booth #326 where we will be showcasing mirrorball

Venue: Seaport World Trade Center, Boston, MA, USA
Date: 1 – 5  May 2017
Booth: #326

We would like to invite you to the following workshop:
Title: High-Throughput Screening for Antibody Discovery Using mirrorball
Presenter: Christyne J. Kane, Senior Scientist, AbbVie Bioresearch Center, Inc.
The antibody discovery industry has begun to set aside traditional assay formats such as ELISA or flow cytometry in favor of more sensitive, high-throughput technologies to screen for novel biologic candidates. This presentation will highlight a selection of multiplex assays for the screening of hybridoma supernatants enabling the discovery process.

Meet mirrorball

TTP Labtech’s mirrorball high sensitivity fluorescence cytometer is a highly versatile instrument that brings process efficiencies to multiple stages in the biologics screening pipeline – from early screening and hit identification, through to characterisation and phenotypic cellular responses.

Key applications include:

  • biologics screening:
    – hybridoma, phage display, B-cell cloning, antibody fragments, peptides, scFv, Fab
  • binding characterisation:
    – Bmaxand Kd determination
  • functional assays:
    – cell health, cell cycle, proliferation, cell signalling
  • quantification of soluble proteins:
    – cytokines, hormones, growth factors

do more antibody screening with less

mirrorball represents a complete biologics screening solution. It offers analysis of bead-bound soluble antigens and cell-surface antigens expressed on both adherent and suspension cell lines in microplates. It is compatible both with washed and no-wash assay formats.

mirrorball’s multiplexing capabilities enable hit determination in high density microplates while simultaneously screening out non-specific and non-selective hits in the same well. This means antibody engineering researchers can identify cross-reactivity and selectivity but – significantly – without the loss of throughput.

Key benefits:

  • a streamlined no-wash assay format
  • unprecedented levels of throughput
  • maintaining cell morphology through in situ analysis of adherent cells
  • investigate multiple targets in one well
  • more stringent results by screening out non-specific and non-selective hits in the same sample
  • assay miniaturisation using high density microplates
  • visual confirmation of your results using an image for QC

Our team can also discuss with you our instruments used for:

  • flexible sample management workflows from ambient to -80°C (comPOUND, arktic, lab2lab)
  • unique low volume, positive displacement liquid handling for any liquid including cells or beads (mosquito, dragonfly).

Want to find out more? We offer a full range of resources, read our application notes and posters here…

application notes:


For more information about the PEGS Boston visit their website here.