What type of analytical instruments can be accessed by the lab2lab system?
To date, LC, LCMS, SFC and NMR instrumentation (from Agilent, Waters and Bruker) have been integrated to a lab2lab system. If other types of instrument are required this could be done with some integration development.
How far away can the instrumentation be from submitting chemist’s laboratory?
We have successfully demonstrated that samples can be transported over 100s of metres which will allow multiple buildings to be connected to a single remote analytical suite.
How many labs and instruments can be connected to the lab2lab system?
The standard system allows 1 instrument to be connected to 28 labs or one lab to 28 instruments and any combination in between. Other combinations are available upon request.
Will I have to modify all my analytical instruments to implement Lab2lab?
No, lab2lab implementation requires no instrument modifications as it uses existing access and interface points.
Will my instrument suppliers still support my equipment if it part of a lab2lab system?
Yes, as there is no modification of the instrumentation, they are for all intents and purposes the same as a standalone system.
If I send a sample for LCMS and I am happy with the result and want to submit to NMR do I have to make up a new solution and submit a second sample?
Providing the LCMS sample is made up in an appropriate solvent (e.g. d6-DMSO) and is of sufficient concentration and volume for data acquisition, the same sample can be sent for NMR after a satisfactory LCMS has been acquired.
Can I recover a sample once submitted into the system for analysis?
Yes on submitting a sample you have a control of its ultimate destination after analysis. It can be sent directly to waste, retained for later collection or remain in the system for additional analysis.
What happens if one of the system’s analytical instruments develops a fault?
The faulty instrument will be isolated and all samples in the system will be redirected to other instrumentation running the required method, whilst the issue is resolved.
Once an instrument is connected to the lab2lab system can it be used offline for other tasks?
Yes, as the lab2lab software monitors for available instruments before sending samples to them, once the equipment has finished offline activities it then becomes available to receive samples from the lab2lab system once again.
What happens if my sample gets stuck in the pipework?
The system is so reliable that this is never likely to happen.
How many samples can I submit to the system at any one time?
The sender units can take up to 9 samples at a time. The buffer can hold 96 samples in an SBS footprint rack. If a greater number of submissions are required then racks of 96 samples can be loaded directly into the buffer module. Robotics can be integrated to allow multiple 96 tube racks to be submitted allowing 24/7 operation.
How long will it take to get data on my sample back?
A matter of a few minutes after sample submission, providing there are enough instruments to cope with the sample submission rate.
If I have a lot of low priority samples to acquire data on, can I load them into the system during the day for them to run during instrument quiet time in the evenings or at weekends?
Yes, registering these samples as low priority at the point of submission will result in them being run once the instrumentation has finished normal priority samples, or at a predefined instrument quiet time.
How is data on my sample returned to me?
Data can be returned in many different ways e.g. as a tradition paper hard copy to a printer, electronically via an e-mail or directly to an electronic lab note book (ELN).
Does lab2lab have access to my analytical data?
No. Lab2lab only detects when data is generated by the instrument.
If I submitted my sample for the wrong method by mistake, can I edit this or will I have to submit another sample to the correct method?
Providing the sample is still within the system, you can edit or add methods, allowing for corrections and additional analyses to be added on the fly.
How can I be sure that the data I receive on my compound is for the sample I submitted and not another chemist’s sample?
Each sample tube has a unique 2 dimensional (2-D) barcode printed on it. This is used to associate the analytical method(s) that the sample is being submitted for with the physical sample at the point of submission. As the sample travels through the system, the 2-D barcode is scanned to ensure that the tube is sent to the correct instrumentation and that the data generated is received by the requesting scientist.